Senate Study Bill 1041 - Introduced SENATE/HOUSE FILE _____ BY (PROPOSED BOARD OF PHARMACY BILL) A BILL FOR An Act relating to controlled substances, including amending 1 certain controlled substances schedules and precursor 2 substances reporting requirements, making penalties 3 applicable, and including effective date provisions. 4 BE IT ENACTED BY THE GENERAL ASSEMBLY OF THE STATE OF IOWA: 5 TLSB 1196DP (7) 90 as/rh

S.F. _____ H.F. _____ Section 1. Section 124.204, subsection 4, Code 2023, is 1 amended by adding the following new paragraphs: 2 NEW PARAGRAPH . ca. Ethyl 2-(1-(5-fluoropentyl)-1H- 3 indazole-3-carboxamido)-3,3-dimethylbutanoate. Other name: 4 5F-EDMB-PINACA. 5 NEW PARAGRAPH . cb. Methyl 2-(1-(5-fluoropentyl)-1H-indole- 6 3-carboxamido)-3,3-dimethylbutanoate. Other names: 7 5F-MDMB-PICA; 5F-MDMB-2201. 8 NEW PARAGRAPH . cc. N-(adamantan-1-yl)-1-(4-fluorobenzyl)- 9 1H-indazole-3-carboxamide. Other names: FUB-AKB48; 10 FUB-APINACA; AKB48 N-(4-FLUOROBENZYL). 11 NEW PARAGRAPH . cd. 1-(5-fluoropentyl)-N-(2-phenylpropan-2- 12 yl)-1H-indazole-3-carboxamide. Other names: 5F-CUMYL-PINACA; 13 SGT-25. 14 NEW PARAGRAPH . ce. (1-(4-fluorobenzyl)-1H-indol-3- 15 yl)(2,2,3,3-tetramethylcyclopropyl) methanone. Other name: 16 FUB-144. 17 NEW PARAGRAPH . cf. 2-(ethylamino)-1-phenylhexan-1-one). 18 Other names: N-Ethylhexedrone; alpha-ethylaminohexanophenone. 19 NEW PARAGRAPH . cg. Alpha-Pyrrolidinohexanophenone. Other 20 names: alpha-PHP; alpha-pyrrolidinohexanophenone; 1-phenyl-2- 21 (pyrrolidin-1-yl)hexan-1-one. 22 NEW PARAGRAPH . ch. 4-Methyl-alpha-ethylaminopentiophenone. 23 Other names: 4-MEAP; 2-(ethylamino)-1-(4-methylphenyl) 24 pentan-1-one. 25 NEW PARAGRAPH . ci. 4’-Methyl-alpha- 26 pyrrolidinohexiophenone. Other names: MPHP; 4’-methyl-alpha- 27 pyrrolidinohexanophenone; 1-(4-methylphenyl)-2- 28 (pyrrolidin-1-yl)hexan-1-one. 29 NEW PARAGRAPH . cj. alpha-Pyrrolidinoheptaphenone. Other 30 names: PV8; 1-phenyl-2-(pyrrolidin-1-yl)heptan-1-one. 31 NEW PARAGRAPH . ck. 4’-Chloro-alpha- 32 pyrrolidinovalerophenone. Other names: 4-chloro-alpha- 33 PVP; 4’-chloro-alpha-pyrrolidinopentiophenone; 34 1-(4-chlorophenyl)-2-(pyrrolidin-1-yl)pentan-1-one. 35 -1- LSB 1196DP (7) 90 as/rh 1/ 4

S.F. _____ H.F. _____ NEW PARAGRAPH . cl. 2-(ethylamino)-2-(3-methoxyphenyl) 1 cyclohexan-1-one. Other names: methoxetamine; MXE. 2 Sec. 2. Section 124.204, subsection 9, Code 2023, is amended 3 by striking the subsection and inserting in lieu thereof the 4 following: 5 9. Other substances. Any material, compound, mixture, 6 or preparation which contains any quantity of the following 7 substances or their optical, positional, and geometric isomers, 8 salts, and salts of isomers: 9 a. Fentanyl-related substances. “Fentanyl-related 10 substance” means any substance not otherwise listed under this 11 schedule or another schedule, and for which no exemption or 12 approval is in effect under section 505 of the federal Food, 13 Drug, and Cosmetic Act that is structurally related to fentanyl 14 by one or more of the following modifications: 15 (1) Replacement of the phenyl portion of the phenethyl group 16 by any monocycle, whether or not further substituted in or on 17 the monocycle. 18 (2) Substitution in or on the phenethyl group with alkyl, 19 alkenyl, akloxyl, hydroxyl, halo, haloalkyl, amino, or nitro 20 groups. 21 (3) Substitution in or on the piperidine ring with alkyl, 22 alkenyl, alkoxyl, ester, ether, hydroxyl, halo, haloalkyl, 23 amino, or nitro groups. 24 (4) Replacement of the aniline ring with any aromatic 25 monocycle whether or not further substituted in or on the 26 aromatic monocycle. 27 (5) Replacement of the N-propionyl group by another acyl 28 group. 29 b. 1-(1-(1-(4-bromophenyl)ethyl)piperidin-4-yl)-1,3- 30 dihydro-2H-benzo[d]imidazole-2-one. Other names: 31 brorphine, 1-[1-[1-(4-bromophenyl)ethyl]-4-piperidinyl]-1, 32 3-dihydro-2H-benzimidazol-2-one. 33 c. 2-(2-(4-butoxybenzyl)-5-nitro-1H-benzimidazol-1- 34 yl)-N,N-diethylethan-1-amine and its isomers, esters, ethers, 35 -2- LSB 1196DP (7) 90 as/rh 2/ 4

S.F. _____ H.F. _____ salts, and salts of isomers, esters, and ethers. Other name: 1 Butonitazene. 2 d. 2-(2-(4-ethoxybenzyl)-1H-benzimidazol-1- 3 yl)-N,N-diethylethan-1-amine and its isomers, esters, 4 ethers, salts, and salts of isomers, esters, and ethers. Other 5 names: Etodesnitazene; etazene. 6 e. N,N-diethyl-2-(2-(4-fluorobenzyl)-5- 7 nitro-1H-benzimidazol-1-yl)ethan-1-amine and its isomers, 8 esters, ethers, salts, and salts of isomers, esters, and 9 ethers. Other name: Flunitazene. 10 f. N,N-diethyl-2-(2-(4-methoxybenzyl)-1H- 11 benzimidazol-1-yl)ethan-1-amine and its isomers, esters, 12 ethers, salts, and salts of isomers, esters, and ethers. Other 13 name: Metodesnitazene. 14 g. N,N-diethyl-2-(2-(4-methoxybenzyl)-5- 15 nitro-1H-benzimidazol-1-yl)ethan-1-amine and its isomers, 16 esters, ethers, salts, and salts of isomers, esters, and 17 ethers. Other name: Metonitazene. 18 h. 2-(4-ethoxybenzyl)-5-nitro-1-(2- 19 (pyrrolidin-1-yl)ethyl)-1H-benzimidazole and its isomers, 20 esters, ethers, salts, and salts of isomers, esters, 21 and ethers. Other names: N-pyrrolidino etonitazene; 22 etonitazepyne. 23 i. N,N-diethyl-2-(5-nitro-2-(4-propoxybenzyl) 24 -1H-benzimidazol-1-yl)ethan-1-amine and its isomers, esters, 25 ethers, salts, and salts of isomers, esters, and ethers. Other 26 name: Protonitazene. 27 Sec. 3. Section 124.210, subsection 3, Code 2023, is amended 28 by adding the following new paragraph: 29 NEW PARAGRAPH . bg. Daridorexant. 30 Sec. 4. Section 124.212, subsection 5, Code 2023, is amended 31 by adding the following new paragraph: 32 NEW PARAGRAPH . g. Ganaxolone (3alpha-hydroxy-3beta-methyl- 33 5alpha-pregnan-20-one). 34 Sec. 5. Section 124B.2, subsection 1, Code 2023, is amended 35 -3- LSB 1196DP (7) 90 as/rh 3/ 4

S.F. _____ H.F. _____ by adding the following new paragraph: 1 NEW PARAGRAPH . ah. Methyl alpha-phenylacetoacetate and 2 its optical isomers. Other names: MAPA; methyl 3-oxo-2- 3 phenylbutanoate. 4 Sec. 6. EFFECTIVE DATE. This Act, being deemed of immediate 5 importance, takes effect upon enactment. 6 EXPLANATION 7 The inclusion of this explanation does not constitute agreement with 8 the explanation’s substance by the members of the general assembly. 9 This bill relates to controlled substances, including 10 amending certain controlled substances schedules and precursor 11 substances reporting requirements. 12 The bill makes changes to controlled substance schedules 13 I, IV, and V in Iowa’s uniform controlled substances Act 14 (Code chapter 124) and to the precursor substances reporting 15 requirement in Code chapter 124B to conform to the specific 16 chemical designations of the substances contained in Title 21 17 of the Code of Federal Regulations, parts 1300, 1308, and 1310. 18 A violation involving a controlled substance included in 19 the bill imposes penalties ranging from a class “B” felony, 20 and in addition to the 25-year mandatory minimum term of 21 imprisonment for class “B” felons, is also punishable by a fine 22 of not less than $5,000 nor more than $100,000; a class “C” 23 felony punishable by imprisonment up to 10 years and a fine of 24 not less than $1,000 nor more than $50,000; to an aggravated 25 misdemeanor punishable by imprisonment up to 2 years and a fine 26 of at least $855 but not more than $8,540. 27 The bill takes effect upon enactment. 28 -4- LSB 1196DP (7) 90 as/rh 4/ 4